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Show HN: I made an open-source Rust program for memory-efficient genomics

logannyeMD Thursday, November 13, 2025

My cofounder and I run a startup in oncology, where we handle cancer genomics data. It occurred to me that, thanks to a recent complexity theory result, there's a clever way to run bioinformatics algorithms using far less RAM. I built this Rust engine for running whole-genome workloads in under 100MB of RAM. Runtime is a little longer as a result - O(TlogT) instead of O(T). But it should enable whole-genome analytics on consumer-grade hardware.

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The article provides an overview of the Rosalind platform, a popular online platform for learning bioinformatics through interactive problems and tutorials. It covers the history, features, and educational approach of the platform, which aims to help students and researchers develop practical skills in computational biology.
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