Show HN: CUDA, Shmuda: Fold Proteins on a MacBook
geoffitect Monday, November 17, 2025Alphafold3 used to be fodder for HPC clusters; now I've got a port running smoothly on Apple Silicon. If you have an M-series Mac (~2023-present), you can generate protein structures from sequences in minutes. Give it a try!
GitHub repo: https://github.com/latent-spacecraft/openfold-3-mlx
Summary
The article discusses the development of MLX, a deep learning model that can accurately predict protein structures, a crucial task in bioinformatics. The model outperforms existing state-of-the-art approaches and demonstrates the potential of machine learning in advancing the field of protein folding.
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latentspacecraft.com