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See also: https://www.businessinsider.com/sergey-brin-says-leaving-goo...

Google co-founder Sergey Brin on leaving retirement to work on AI - https://news.ycombinator.com/item?id=37226292 - Aug 2023 (25 comments)

Back at Google Again, Cofounder Sergey Brin Just Filed His First Code Request - https://news.ycombinator.com/item?id=34645311 - Feb 2023 (16 comments)

I used Tailscale, an old laptop, Claude Code, and Termius to code from my phone anywhere I have Internet connection.

Great for parties where you rather be home tinkering.

The article discusses the author's experience with a Snapdragon Developer Kit from Microsoft, which stopped working after a software update, leaving the author unable to use the device. The article explores the challenges faced in troubleshooting and resolving the issue with Microsoft's support.

The article discusses the release of Opus 4.5, a major update to the Opus open-source audio codec. It highlights the significant changes in this version, including improved quality, increased efficiency, and expanded support for various audio formats and platforms.

pdf: https://download.ssrn.com/2026/1/6/5877662.pdf?response-cont...

The article discusses the importance of instructional design in creating effective online learning experiences. It highlights the key principles and best practices for designing engaging and learner-centered digital courses.

A fast SOCKS5 proxy that tunnels your traffic through what looks like normal SMTP email, bypassing Deep Packet Inspection firewalls.

How it works: - Client runs a local SOCKS5 proxy (127.0.0.1:1080) - Traffic is sent to server disguised as SMTP (EHLO, STARTTLS, AUTH) - DPI sees legitimate email session, not a VPN/proxy

Features: - One-liner install on any Linux VPS - Multi-user with per-user secrets and IP whitelists - Auto-generated client packages (just double-click to run) - Auto-reconnect on connection loss - Works with any app that supports SOCKS5

Tech: Python/asyncio, TLS 1.2+, HMAC-SHA256 auth

GitHub: https://github.com/x011/smtp-tunnel-proxy

The article discusses inheritance, a fundamental concept in object-oriented programming (OOP). It explains how inheritance allows a subclass to inherit properties and methods from a superclass, enabling code reuse and creating a hierarchy of related classes.

The article discusses the role of the oral microbiome and the potential benefits of probiotics, such as BioGaia's Prodentis, in maintaining oral health. It covers the importance of a balanced oral microbiome and how probiotic supplements can help promote a healthy mouth and prevent issues like gum disease.

The article describes how the Adafruit team recreated Steve Jobs' 1975 Atari horoscope program, allowing readers to run the original program in their web browser. It provides insights into Jobs' early programming experiences and the historical significance of this project.

Vietnam has banned unskippable ads and requires a skip button to appear after 5 seconds, in an effort to improve the online advertising experience for consumers.

This article provides an in-depth exploration of computer programming, explaining the fundamentals of code, its history, and the evolution of the software development industry. It offers a comprehensive guide for both technical and non-technical readers to understand the significance and inner workings of code in the modern digital landscape.

I've spent the last few months working on something I wish I'd had years ago. I kept running into the same issue: CI green, production mail broken. TLS handshake failures, DKIM alignment mismatches, SPF soft-fails ... the stuff that only surfaces when real mail servers are involved. Most test tools (Mailpit, MailHog) are catch-alls. They confirm "an email was sent" but don't validate the protocol. They also aren't designed for network-exposed environments: no auth, unprotected Web UI, easy to enumerate messages.

VaultSandbox is my attempt at fixing that. It's a self-hosted SMTP gateway (AGPLv3) that validates SPF, DKIM, DMARC, and rDNS on every incoming message. You keep your production email provider (Postmark, SendGrid, SES) in tests and you just change the recipient domain. No mocking, no config changes. There are client SDKs (Node, Python, Go, Java, .NET), plus a Web UI and a CLI for manual testing.

Some technical details:

Deterministic Tests Instead of polling or sleep loops, the SDKs use Server-Sent Events (SSE) so test assertions trigger the moment the mail hits the gateway.

Minimal infrastructure footprint Built with NestJS and Angular, with no external database dependency to keep the container footprint small and easier to reason about.

Post-Quantum Encryption I use ML-KEM-768 for the encryption layer. Incoming mail is encrypted immediately using a client-generated public key and the plaintext is discarded. The server only ever stores encrypted message data and cannot decrypt it. I chose PQ because I wanted to build something I wouldn't have to revisit in five years. If it handles large PQ keys reliably, everything else is easy.

Quick start: https://vaultsandbox.dev/getting-started/quickstart/

Site: https://vaultsandbox.com

I'd love feedback, especially on whether AGPLv3 would be a blocker for something you'd self-host in dev.

The article discusses AMD's announcements at CES 2026, including details about their latest processors and graphics cards. It covers the company's advancements in performance, power efficiency, and support for new technologies.

The article describes the author's journey of building a custom camera after not finding the features they wanted in existing models. It highlights the challenges and process involved in designing and constructing a unique camera that meets their specific needs.

The article explores the mathematical approaches of Alexander Grothendieck, a prominent 20th-century mathematician, highlighting his emphasis on conceptual thinking, categorical frameworks, and his influence on the development of modern mathematics.

This article discusses the five main Java Virtual Machine (JVM) issues, dubbed the 'Five Knights of the MCP Apocalypse', that can significantly impact the performance and stability of Java applications. The article provides an overview of these issues, including out-of-memory errors, lock contention, garbage collection, CPU saturation, and thread starvation, and offers insights into how to identify and mitigate these problems.

WSJ writeup ("AI Hackers Are Coming Dangerously Close to Beating Humans"): https://www.wsj.com/tech/ai/ai-hackers-are-coming-dangerousl..., https://archive.ph/L4gh3

Hi HN, we're Deniz and Sherry from Tamarind Bio (https://www.tamarind.bio). Tamarind is an inference provider for AI drug discovery, serving models like AlphaFold. Biopharma companies use our library of leading open-source models to design new medicines computationally.

Here’s a demo: https://youtu.be/luoMApPeglo

Two years ago, I was hired at a Stanford lab to run models for my labmates. Some post-doc would ask me to run a set of 1-5 models in sequence with tens of thousands inputs and I would email them back the result after setting up the workflow in the university cluster.

At some point, it became unreasonable that all of an organization's computational biology work would go through an undergrad, so we built Tamarind as a single place for all molecular AI tools, usable at massive scale with no technical background needed. Today, we are used by much of the top 20 pharma, dozens of biotechs and tens of thousands of scientists.

When we started getting adoption in the big pharma companies, we found that this problem also persisted. I know directors of data science, where half their job could be described as running scripts for other people.

Lots of companies have also deprecated their internally built solution to switch over, dealing with GPU infra and onboarding docker containers not being a very exciting problem when the company you work for is trying to cure cancer.

Unlike non-specialized inference providers, we build both a programmatic interface for developers along with a scientist-friendly web app, since most of our users are non-technical. Some of them used to extract proteins from animal blood before replacing that process with using AI to generate proteins on Tamarind.

Besides grinding out images for each of the models we serve, we’ve designed a standardized schema to be able to share each model’s data format. We’ve built a custom scheduler and queue optimized for horizontal scaling (each inference call takes minutes to hours, and runs on one GPU at a time), while splitting jobs across CPUs and GPUs for optimal timing.

As we've grown to handle a substantial portion of the biopharma R&D AI demand on behalf of our customers, we've expanded beyond just offering a library of open source protocols.

A common use case we saw from early on was the need to connect multiple models together into pipelines, and having reproducible, consistent protocols to replace physical experiments. Once we became the place to build internal tools for computational science, our users started asking if they could onboard their own models to the platform.

From there, we now support fine-tuning, building UIs for arbitrary docker containers, connecting to wet lab data sources and more!

Reach out to me at deniz[at]tamarind.bio if you’re interested in our work, we are hiring! Check out our product at https://app.tamarind.bio and let us know if you have any feedback to support how the biotech industry uses AI today.

The article discusses a bill introduced in Congress by Rep. Marjorie Taylor Greene that aims to eliminate the H-1B visa program, which allows U.S. companies to temporarily employ foreign workers in specialty occupations. The bill is part of a broader effort by some lawmakers to restrict immigration and protect American jobs.

The article presents a novel deep learning model for image classification, which leverages a multi-scale attention mechanism to achieve state-of-the-art performance on various benchmark datasets. The proposed approach outperforms existing methods in terms of accuracy and computational efficiency.

I created a small webapp, to create simple audio loops online. A bit rough around the edges but gets you started in less than 10 seconds on creating loops.

Laylo, a YC-backed company, is seeking a Head of Growth to lead their expansion efforts. The successful candidate will be responsible for developing and executing growth strategies to increase the company's user base and revenue.

This article explores the growing trend of people becoming increasingly fatigued with social media, citing concerns such as privacy issues, negativity, and the desire for more authentic connections. It suggests that this shift may lead to a more balanced and thoughtful approach to online engagement.

Hey HN! I'm Akshay, and I'm launching Seer - yet another AI workflow builder with granular OAuth scopes.

GitHub: https://github.com/seer-engg/seer Demo video: https://youtu.be/cmQvmla8sl0

The Problem: We've been building AI workflows for the past year and kept running into the same issue: existing platforms (n8n, Langflow, Flowise) require full access to your Google services even for read-only operations. Want to summarize emails? You're also granting send permissions. Want to read docs? You're also granting edit permissions. If you want granular scopes, the onus is on you to:

- Create your own OAuth app with Google (1-2 weeks approval time) - Modify source code to support read-only scopes

We saw this pattern repeated across Discord channels and GitHub issues - developers asking for better scope support, maintainers saying "you can configure it yourself."

Our Solution: Seer ships with read-only auth scopes as the default for common operations. It's self-hostable, so your data never leaves your infrastructure. The demo shows a simple email summarization workflow (Gmail + LLM API), but the principle applies to any integration.

Why This Matters: Security through least privilege isn't just best practice - it's essential when you're giving AI agents access to your production data. One compromised workflow shouldn't mean your entire Google Workspace is at risk.

Questions for HN: 1. How are you currently handling OAuth scopes in your AI automation workflows? 2. Would you find value in a scope validator that audits your existing workflows? 3. What other integrations would you want to see with granular permissions?

The only similar platform with granular scope support is Make.com, but it's closed-source. We think this should be the standard, not the exception.

Would love your feedback!

The article discusses a technique using GeoSpy AI to rapidly locate a vehicle in a photo by analyzing its geospatial data and visual attributes. The process can identify the vehicle's location in under 30 seconds, demonstrating the potential of AI-powered geospatial analysis for various applications.

The article presents an experiment called 'PassSeeds' that explores the possibility of hijacking passkeys, a new authentication technology, to unlock various cryptographic use cases beyond simple authentication. The experiment investigates the potential security implications and challenges of extending the functionality of passkeys beyond their original purpose.